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Network-guided sparse regression modeling for detection of gene-by-gene interactions

✍ Scribed by Lu, C.; Latourelle, J.; O'Connor, G. T.; Dupuis, J.; Kolaczyk, E. D.


Book ID
121495262
Publisher
Oxford University Press
Year
2013
Tongue
English
Weight
267 KB
Volume
29
Category
Article
ISSN
1367-4803

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## Abstract The detection of genotypes that predict common, complex disease is a challenge for human geneticists. The phenomenon of epistasis, or gene‐gene interactions, is particularly problematic for traditional statistical techniques. Additionally, the explosion of genetic information makes exha