## Abstract ## Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease caused by loss of immunologic self tolerance and characterized by chronic joint inflammation. Adult mesenchymal stem cells (MSCs) were recently found to suppress effector T cell responses and to have beneficial effe
β¦ LIBER β¦
Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis
β Scribed by Dos Santos, Claudia; Murthy, Srinivas; Hu, Pingzhao; Shan, Yuexin; Haitsma, Jack; Mei, Shirley; Stewart, Duncan; Liles, Conrad
- Book ID
- 118173857
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 48 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0883-9441
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## Abstract Human T cells require two discrete signals to initiate their proliferation. In Jurkat T cells the first signal can be provided by the phorbol ester TPA and the second by the calcium ionophore A23187. We have isolated a cDNA from Jurkat T cells representing mRNA induced by TPA but inhibi