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• Book ID: 104306859
• Publisher: Elsevier Science
• Year: 1998
• Tongue: English
• Weight: 150 KB
• Volume: 28
• Category: Article
• ISSN: 0167-9473
• DOI: 10.1016/s0167-9473(98)90067-6

✦ Synopsis

Monitoring of Clinical Trials", discusses how group-sequential designs provide useful guidelines that enable one to satisfy the valid objectives of interim monitoring while avoiding undesirable consequences in a flexible manner. Throughout the article the authors stress the need for flexibility. The EaSt software supports this philosophy and makes its implementation practical.