𝔖 Bobbio Scriptorium
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Nerve regeneration in diabetic rats

✍ Scribed by Srdan Babovic; Andrew M. Ress; A. Lee Dellon; Michael F. Angel; Michael J. Im; Paul N. Manson

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
34 KB
Volume
18
Category
Article
ISSN
0738-1085

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✦ Synopsis

This study evaluated the capacity of diabetic rats to recover the ability to walk after nerve repair or nerve graft of the posterior tibial nerve at thigh level. Functional recovery of the posterior tibial nerve was evaluated by walking track analysis during regeneration in streptozotocin-induced diabetic rats. Surgical procedures were performed 8 weeks after induction of diabetes. The nerve repair was epineurial. The nerve graft was a 1.5 cm segment orthotopically replaced. There was no significant difference in functional recovery between normal and diabetic rats for both the nerve repair and nerve graft groups at 6, 12, and 24 weeks after nerve reconstruction. It is concluded that the presence of diabetes is not a contraindication for nerve reconstruction.

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