Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons
โ Scribed by Lindsay, Ronald M.; Harmar, Anthony J.
- Book ID
- 109757745
- Publisher
- Nature Publishing Group
- Year
- 1989
- Tongue
- English
- Weight
- 382 KB
- Volume
- 337
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/337362a0
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The Oct-2 transcription factor has a predominantly inhibitory effect on gene expression in neuronal cell lines. This factor and its corresponding mRNA have previously been shown to be elevated in adult rat dorsal root ganglion (DRG) neurons chronically exposed to nerve growth factor (NGF). Here we s