Nerve growth factor-mediated increase of the substance P content of chick embryo dorsal root ganglia
β Scribed by J.P. Schwartz; E. Costa
- Book ID
- 118865387
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 280 KB
- Volume
- 170
- Category
- Article
- ISSN
- 0006-8993
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## Abstract Recently we have shown that nerve growth factor (NGF) influences the coupled movements of Na^+^ and K^+^ across the membrane of chick embryo dorsal root ganglion (DRG) and other target cells. These ionic effects of NGF are consistent with a model in which NGF acts through the classical
## Abstract Nerve growth factor (NGF) is required for the growth and development of sensory and sympathetic neurons. Incubation of chick dorsal root ganglionic cells without NGF resulted in a decrease of active (Na^+^, K^+^βpumpβmediated) K^+^ influx over a period of several hours. Addition of NGF