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Nerve growth factor induces the expression of the LIM homeodomain transcription factor Isl-1 with the kinetics of an immediate early gene in adult rat dorsal root ganglion

โœ Scribed by H.L. Jameson; K.A. Lillycrop


Book ID
117471966
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
188 KB
Volume
309
Category
Article
ISSN
0304-3940

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The Oct-2 transcription factor has a predominantly inhibitory effect on gene expression in neuronal cell lines. This factor and its corresponding mRNA have previously been shown to be elevated in adult rat dorsal root ganglion (DRG) neurons chronically exposed to nerve growth factor (NGF). Here we s