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Nerve growth factor induces Fos-like immunoreactivity within identified cholinergic neurons in the adult rat basal forebrain

โœ Scribed by Robert B Gibbs; Christianna Martynowski


Book ID
114002413
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
391 KB
Volume
753
Category
Article
ISSN
0006-8993

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Nerve growth factor (NGF) is a potential treatment for cholinergic dysfunction associated with Alzheimer's disease (AD). In rats, NGF activates gene expression of the acetylcholine synthetic enzyme choline acetyltransferase (ChAT) and prevents age-and lesion-induced degeneration of basal forebrain (