## Abstract Nephrogenic systemic fibrosis (NSF) has now been linked to gadoliniumβbased contrast (GBC) exposure in those with compromised kidney function, particularly those with endβstage renal disease (ESRD). When ESRD is present, symptoms can be quite devastating for the patient including severe
Nephrogenic systemic fibrosis: The need for accurate case reporting
β Scribed by Alberto Spinazzi; Miles A. Kirchin; Gianpaolo Pirovano
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 36 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
β¦ Synopsis
We have read with great interest the recent editorial by Dr. Peter Dawson entitled "Nephrogenic Systemic Fibrosis: Possible Mechanisms and Imaging Management Strategies" which appeared in the October issue of the Journal of Magnetic Resonance Imaging (1). Although the article is well written, there are shortcomings which should be brought to the attention of the readers of JMRI to prevent misconceptions and misunderstandings. Above all, Table 1 indicates that there have been cases of nephrogenic systemic fibrosis (NSF) with certain gadolinium-based contrast agents (GBCAs) only. Unfortunately, it is not clear whether Table 1 refers to cases spontaneously reported by healthcare professionals or by consumers to the healthcare authorities ("spontaneous reports") or cases described in peer-reviewed articles. In our experience, several spontaneous reports, especially those reported by consumers, turn
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## Abstract Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis (NFD/NSF) is a recently recognized systemic fibrosing disorder that develops in the context of renal insufficiency. Its predominant manifestation is severe cutaneous fibrosis, often causing disabling contractures of neighbor
## Abstract ## Purpose To examine the positive reporting bias regarding the link with gadolinium (Gd) exposure and nephrogenic systemic fibrosis (NSF) in patients with renal impairment. This link has impacted strongly the international radiology safety guidelines. We believe that positive reportin