Nephrogenic fibrosing dermopathy: A rare entity in patients awaiting liver transplantation

✍ Scribed by Henry Chiu; Gregory Wells; Henry Carag; Erica Canova; Roberto J. Firpi

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 182 KB
• Volume: 10
• Category: Article
• ISSN: 1527-6465
• DOI: 10.1002/lt.20068

✦ Synopsis

A 56-year-old Caucasian female with end-stage liver disease secondary to ␣1-antitrypsin deficiency and end-stage renal disease secondary to idiopathic membranous nephropathy presented with a one-week history of increased bilateral lower extremity edema and anasarca. On admission, the patient complained of raised hardened areas especially prominent on the upper medial thighs that were painful, warm, and nonpruritic. She denied any constitutional symptoms and denied using any new medications. On exam, the patient was found to be afebrile with stable oxygen saturation. The abdomen was distended with evidence of hepatomegaly. Bilateral lower extremity edema to the groin were present, and hyperpigmented plaques (Fig. 1) (tender, indurated, and warm) were noted on the upper medial aspects of her thighs, but not involving the groin. There was no visible face or upper extremity involvement.

Laboratory tests did not reveal leukocytosis or eosino-