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Nephrogenic diabetes insipidus due to hydronephrosis in a patient with a solitary kidney

✍ Scribed by Katsunobu Yoshioka; Masahito Imanishi; Haruna Sakai; Takashi Morikawa; Noriyuki Okada; Yoshio Konishi; Shiro Tanaka; Sadanori Kamikawa; Taku Kim; Satoru Fujii


Publisher
Springer
Year
2003
Tongue
English
Weight
302 KB
Volume
7
Category
Article
ISSN
1342-1751

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The function of small GTPases is fine-tuned by a complex network of regulatory proteins such as GTPase-activating proteins. The C1 gene at Xq28 encodes a protein assumed to function as a Rho GTPase-activating protein (rhoGAP). Characterization of the molecular defect causing X-linked nephrogenic dia