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Neoplastic transformation induced by a direct perturbation of DNA

โœ Scribed by Barrett, J. Carl; Tsutsui, Takeki; Ts'o, Paul O. P.

Book ID
109710119
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
403 KB
Volume
274
Category
Article
ISSN
0028-0836

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## Abstract Manganese superoxide dismutase (MnSOD) scavenges toxic superoxide radicals produced in the mitochondria. Transfection of the human MnSOD gene into mouse C3H 10T1/2 cells resulted in production of active MnSOD, which was properly transported into mitochondria. Overexpression of MnSOD pro