Cell motility is induced by many growth factors acting through cognate receptors with intrinsic tyrosine kinase activity (RPTK). However, most of the links between receptor activation and the biophysical processes of cell motility remain undeciphered. We have focused on the mechanisms by which the E
Neoplasms associated with alterations in fibroblast growth factor receptors
โ Scribed by Cohen, M. Michael
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 58 KB
- Volume
- 119A
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## Objective To investigate the molecular mechanism of the overexpression of transforming growth factor ฮฒ receptors (TGFฮฒRs) in dermal fibroblasts from patients with systemic sclerosis (SSc). ## Methods Dermal fibroblasts from 7 patients with diffuse SSc of recent onset and from 7 he
Fibroblast growth factor receptor (FGFR) mutations have been found in craniosynostosis syndromes with and without limb and/ or dermatologic anomalies. Ocular manifestations of FGFR2 syndromes are reported to include shallow orbits, proptosis, strabismus, and hypertelorism, but no ocular anterior cha
The development and progression of invasive uterine cervical carcinomas appear to be associated with the progressive loss of sensitivity to transforming growth factor-โค (TGFโค)mediated cell cycle arrest. In order to identify possible molecular mechanisms responsible for TGFโค resistance, we screened t