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Neonatal phenobarbital administration results in increased cytochrome P450-dependent monooxygenase activity in adult male and female rats

โœ Scribed by D.M. Bagley; J.R. Hayes


Book ID
115756595
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
359 KB
Volume
114
Category
Article
ISSN
0006-291X

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The influence of both single and concurrent administration of phenobarbital and clofibrate on hepatomegaly, cytochrome P450-dependent mixed function oxidase activities, and peroxisome proliferation in male rat liver have been studied. Both xenobiotics separately increase the liver: body weight ratio