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Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats

โœ Scribed by Yuichiro Watanabe; Shinya Hashimoto; Akiyoshi Kakita; Hitoshi Takahashi; Jan Ko; Makoto Mizuno; Toshiyuki Someya; Paul H Patterson; Hiroyuki Nawa

Book ID
116774449
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
369 KB
Volume
48
Category
Article
ISSN
0168-0102

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Leukemia inhibitory factor prevents the
Leukemia inhibitory factor prevents the death of axotomised sensory neurons in the dorsal root ganglia of the neonatal rat
โœ S. S. Cheema; L. Richards; M. Murphy; P. F. Bartlett ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 622 KB

Leukemia inhibitory factor (LIF) has several characteristics of a neurotrophic factor for sensory neurons. Here we have investigated whether LIF also supports the survival of axotomised sensory neurons in vivo. Newborn rat pups received a unilateral sciatic nerve transection and the injury site was