## Abstract Recent evidence points to an association between intrauterine infection and cerebral palsy (CP) in the preterm as well as the term infant. The mechanisms that link these two conditions are unclear. Chorioamnionitis is a common clinical problem complicating 5β10% of pregnancies, whereas
β¦ LIBER β¦
Neonatal encephalopathy in the term infant: Neuroimaging and inflammatory cytokines
β Scribed by Foster-Barber, Audrey ;Ferriero, Donna M.
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 97 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1080-4013
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β¦ Synopsis
Abstract
The interrelationship between inflammation and ischemia is complex and poorly understood in the developing nervous system. In the preterm newborn, maternal infection may predispose to white matter injury and may be associated with cytokine elevation. In the term infant, few studies exist linking elevation of cytokines with encephalopathy and poor neurodevelopmental outcome. This review discusses the interplay among inflammatory cytokines, neonatal encephalopathy, and neuroimaging parameters. MRDD Research Reviews 2002;8:20β24. Β© 2002 WileyβLiss, Inc.
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