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Neonatal alloimmune thrombocytopenia caused by human leucocyte antigen-B27 antibody

✍ Scribed by H. Thude; U. Schorner; C. Helfricht; M. Loth; B. Maak; D. Barz

Book ID: 110868843
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 122 KB
Volume: 16
Category: Article
ISSN: 0958-7578
DOI: 10.1111/j.1365-3148.2006.00634.x

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## Abstract Neonatal alloimmune thrombocytopenia (NAIT) is the most common cause of severe thrombocytopenia and intracranial hemorrhage in the perinatal period. While the gold standard for making a diagnosis of NAIT is detection of a human platelet antigen (HPA)‐specific antibody in maternal serum,