Neomembranes: A concept review with special reference to self-reinforced polyglycolide membranes
✍ Scribed by Ashammakhi, N. A.
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 898 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0021-9304
No coin nor oath required. For personal study only.
✦ Synopsis
Absorbable implants are being increasingly used in various fields of medicine. Important materials for these applications include the polyesters polylactide and polyglycolide. Following implantation of any absorbable device there occurs a proliferation of fibrous tissue, which along with material from the degrading implant forms a composite membranous structure-a neo- membrane. Neomembranes can be exploited in guiding tissue regeneration. Success in this respect has been achieved in treatment of bone defects, nerve defects, and periodontal ligaments. Future research may ultimately permit taking advantage of neomembranes in the reconstruction of more complex organs such as the liver. Gaining an understanding of implant characteristics and implant-tissue interaction is essential for further progress in this area. 0 1996 John Wiley & Sons, Inc.
I
The growing use of absorbable implants makes it important to gain as much understanding as possible about the interaction between tissues and the biomaterials used in these applications. Tissue-implant interaction typically stimulates creation of a composite membranous structure, here defined as a neornembrane. A neomembrane may take the form of a capsule that may persist, in the case of a biostable implant, or, in the case of an absorbable implant, ultimately replace the device itself. A neomembrane usually follows the form of the implant. A membranous, flat implant, for instance, stimulates the formation of a flat neomembrane (Fig. 1 ) .