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Neoadjuvant Therapy for HER-2/neu–Expressing Ductal Carcinoma in Situ Using Type 1 Polarized Dendritic Cell Vaccines

✍ Scribed by Czerniecki, Brian J.; Xu, Min; Koski, Gary

Book ID: 122055770
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 318 KB
Volume: 17
Category: Article
ISSN: 1043-321X
DOI: 10.1016/S1043-321X(07)80102-0

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## Abstract This study was designed to determine whether the vaccination of genetically modified dendritic cells (DCs) simultaneously expressing carcinoembryonic antigen (CEA), granulocyte macrophage colony‐stimulating factor (GM‐CSF) and interleukin 12 (IL‐12) can overcome the peripheral T‐cell to