The team of Liu et al. generated endoderm-derived human induced pluripotent stem (iPS) cells from primary hepatocytes. 1 However, they generated human iPS cells by using viral transgenes. 1 Clinical applications of human iPS cells require avoiding viral transgenes. On the other hand, the reprogrammi
Neoadjuvant therapies for hepatocellular carcinoma before liver transplantation: A critical appraisal
โ Scribed by Patricia M. Lopez; Augusto Villanueva; Sasan Roayaie; Josep M. Llovet
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 133 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1527-6465
- DOI
- 10.1002/lt.21018
No coin nor oath required. For personal study only.
โฆ Synopsis
Hepatocellular carcinoma (HCC) is a major health problem, being the fifth most common cancer worldwide. 1 The incidence of HCC is increasing in Europe and the United States, 2 and it is currently the leading cause of death among patients with cirrhosis. 3 The advent of surveillance programs has led to a change in the stage of tumors detected. In more than half of the cases, these tumors will be suitable for potentially curative treatments, such as resection, transplantation, and percutaneous ablation. 4,5
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