𝔖 Bobbio Scriptorium
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Neoadjuvant strategies for the treatment of locally advanced esophageal cancer

✍ Scribed by John R. Hyngstrom; Mitchell C. Posner


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
85 KB
Volume
101
Category
Article
ISSN
0022-4790

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✦ Synopsis


Abstract

Patients with locally advanced esophageal carcinoma have consistently poor survival following surgery with associated high systemic and local‐regional failure rates. Neoadjuvant therapeutic strategies have been employed in an attempt to improve outcome with variable success. Randomized trials of either neoadjuvant chemotherapy or chemoradiotherapy have shown conflicting results regarding survival and local‐regional control. Future efforts should focus on identifying novel agents and targets to improve therapeutic efficacy. J. Surg. Oncol. 2010; 101:299–304. Β© 2010 Wiley‐Liss, Inc.


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