Background and Objectives: Since the prognosis of patients with T4 squamous cell carcinoma (SCC) of the esophagus is extremely poor, an effective multimodal treatment needs to be established. Methods: Forty-five patients with SCC of the esophagus at the T4 classification of the disease but no hemato
Neoadjuvant Concurrent Chemoradiation Therapy Followed by Definitive High-dose Radiation Therapy or Surgery for Operable T3 Squamous Cell Carcinoma of Thoracic Esophagus
β Scribed by Ishida, Y.; Negoro, Y.; Fujii, T.; Kusumi, F.; Asao, Y.
- Book ID
- 122948032
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 52 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0360-3016
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## Abstract ## Background Radiation therapy (RT) is commonly used in the management of patients with advanced (T3βT4) oropharyngeal squamous cell carcinomas. In recent years, based upon the metaβanalyses of randomized trials, chemotherapy administered concurrently with RT (chemoradiotherapy) has b
Twenty-four previously untreated patients with primary inoperable squamous cell carcinoma of the esophagus showing no evidence of hematogenous metastasis were treated with concurrent chemotherapy and radiation therapy (CRT) followed by surgical resection if possible. The chemotherapy regimen consist