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Nelfinavir and indinavir reduce oral clearance of amprenavir

Book ID
120861603
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2002
Weight
133 KB
Volume
1359
Category
Article
ISSN
1173-8324

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Simultaneous determination of six HIV pr
Simultaneous determination of six HIV protease inhibitors (amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir), the active metabolite of nelfinavir (M8) and non-nucleoside reverse transcriptase inhibitor (efavirenz) in human plasma by high-performance liquid chromatography
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We report the development of a simple, economical and reliable chromatographic method for the simultaneous determination of six HIV protease inhibitors (PIs; amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir), the active metabolite of nelfinavir (M8) and the non-nucleoside rever