Neisseria gonorrhoeaeRNA/DNA hybridization and culture for screening of gonococcal infections in a low-prevalence population
✍ Scribed by Patrice Sednaoui; Jean-Elie Malkin; Jean-Michel Alonso
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 365 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0393-2990
No coin nor oath required. For personal study only.
✦ Synopsis
Gonorrhea is still a major sexually transmitted disease (STD) worldwide. Its etiologic diagnosis is based on identification of the causative agent, Neisseria gonorrhoeae, by culture of genital secretions, which is often hampered by difficulties of sample collection and transport. Alternatively, nucleic acid hybridization techniques for routine diagnosis of N. gonorrhoeae appear to be useful by eliminating problems associated with bacterial viability, particularly for surveillance of low-prevalence populations. Our study among 1,508 outpatients undergoing routine examination for common STDs used RNA/DNA hybridization with a DNA probe