Human T cells express HLA class I1 antigens upon activation. Although activated, class II+ Tcells can present alloantigens under certain circumstances, the functional role of class I1 antigens on activated T cells remains largely unknown. Here, we report that cross-linking of HLA-DR molecules expres
โฆ LIBER โฆ
Negative signal transmission through class II molecules on activated T cells
โ Scribed by Urban, Nancy D.; Zier, Karen S.
- Book ID
- 122671609
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 841 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0198-8859
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## HLA class I1 molecules on monocytes regulate T cell proliferation through physical interaction in the CD3 activation pathway* HLA class I1 molecules are involved in the OKT3-induced Tcell activation, since monoclonal antibodies (mAb) to monomorphic determinants of class I1 antigens are able to