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Negative Regulation of JAK-STAT Signaling and Heart Failure

✍ Scribed by Hideo Yasukawa; Toyoharu Oba; Yusuke Sugi; Tsutomu Imaizumi

Book ID
116338920
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
44 KB
Volume
14
Category
Article
ISSN
1532-8414

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Negative regulation of the JAK/STAT path
Negative regulation of the JAK/STAT pathway
✍ Robyn Starr; Douglas J. Hilton πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 89 KB πŸ‘ 2 views

Cytokines induce a variety of biological responses by binding to specific cell surface receptors and activating cytoplasmic signal transduction pathways, such as the JAK/STAT pathway. Although these responses are generally transient, few molecules have been characterised that switch the signal off.