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Negative growth control by a novel low Mr phosphotyrosine protein phosphatase in normal and transformed cells

โœ Scribed by Marco Ruggiero; Claudia Pazzagli; Stefania Rigacci; Lucia Magnelli; Giovanni Raugei; Andrea Berti; Vincenzo P. Chiarugi; Jacalyn H. Pierce; Guido Camici; Giampietro Ramponi


Book ID
115928828
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
452 KB
Volume
326
Category
Article
ISSN
0014-5793

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Overexpression of a synthetic phosphotyr
โœ Giampietro Ramponi; Marco Ruggiero; Giovanni Raugei; Andrea Berti; Alessandra Mo ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 567 KB

We studied the level of the cytosolic phosphotyrosine protein phosphatase (PTPase) (originally termed low-M, acid phosphatase) in normal NIH/3T3 and in v-erbB-transformed fibroblasts. The level of the enzyme, assayed by ELISA, was inversely related to cell proliferation, normally growing cells had l