✦ LIBER ✦

Negative epistasis between the malaria-protective effects of α+-thalassemia and the sickle cell trait

✍ Scribed by Williams, Thomas N; Mwangi, Tabitha W; Wambua, Sammy; Peto, Timothy E A; Weatherall, David J; Gupta, Sunetra; Recker, Mario; Penman, Bridget S; Uyoga, Sophie; Macharia, Alex

Book ID: 109919252
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 177 KB
Volume: 37
Category: Article
ISSN: 1061-4036
DOI: 10.1038/ng1660

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Protective effects of the sickle cell ge

Protective effects of the sickle cell gene against malaria morbidity and mortality

✍ Michael Aidoo; Dianne J Terlouw; Margarette S Kolczak; Peter D McElroy; Feiko O 📂 Article 📅 2002 🏛 The Lancet 🌐 English ⚖ 69 KB

The effect of Hb F and α-thalassemia on

The effect of Hb F and α-thalassemia on the red cell indices in sickle cell anemia

✍ Paul F. Milner; George J. Garbutt; L. V. Nolan-Davis; Felix Jonah; Lois B. Wilso 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 757 KB

Effects of α-thalassemia-2 on the develo

Effects of α-thalassemia-2 on the developmental changes of hematological values in children with sickle cell disease from georgia

✍ A. E. Felice; K. M. McKie; M. P. Cleek; E. M. Marino; A. Kutlar; V. C. McKie 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 723 KB

Age-dependent changes in the membrane su

Age-dependent changes in the membrane surface area: sickle red blood cell volume may account for differential clinical effects of coinherited α thalassemia on sickle cell anemia

✍ Stephen H. Embury 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 56 KB

Effect of α-thalassemia and β-globin gen

Effect of α-thalassemia and β-globin gene cluster haplotypes on the hematological and clinical features of sickle-cell anemia in Brazil

✍ Figueiredo, M.S.; Kerbauy, J.; Gonçalves, M.S.; Arruda, V.R.; Saad, S.T.O.; Sona 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 447 KB 👁 1 views

To compare the features of sickle-cell anemia in Brazil with those in other locales, we studied the effects of the p-globin-like gene cluster haplotype and a-thalassemia upon the clinical and hematological features in 85 patients. The distribution of haplotypes differed from that in the United State

Protection against severe clinical manif

Protection against severe clinical manifestations of Plasmodium falciparum malaria among sickle cell trait subjects is due to modification of the release of cytokines and/or cytoadherence of infected erythrocytes to the host vascular beds

✍ N.H Abdulhadi 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 80 KB