𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Negative costimulatory molecules: The proximal of regulatory T cells?

✍ Scribed by Nianqiao Gong; Yongxiang Zhao; Chong Dong; Zhonghua Klaus Chen

Book ID
116743284
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
173 KB
Volume
67
Category
Article
ISSN
0306-9877

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T lymphocytes require two distinct signals for activation from antigen presenting cells . The first antigen-specific signal occurs when the T-cell receptor binds to antigenic peptides presented by major histocompatibility complex molecules. The second costimulatory signal occurs when CD28 and CTLA-4