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Negative Chronotropic Effect of Botulinum Toxin on Neonatal Rat Cardiac Myocytes

✍ Scribed by Koichi Kimura; Hisakazu Kimura; Noriko Yokosawa; Hiroshi Isogai; Emiko Isogai; Shunji Kozaki; Atsushi Miyamoto; Takeshi Nishikawa; Hideyo Ohshika; Toru Kubota; Nobuhiro Fujii

Book ID
115581693
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
133 KB
Volume
244
Category
Article
ISSN
0006-291X

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The effects of culture and membrane potential on Go alpha 39 expression were examined in neonatal rat cardiac myocytes. During six days of culture, the amount of Go alpha 39 in myocytes increased six-fold. The increase in Go alpha 39 appeared to be programmed, since Go alpha 39 of rat hearts also in