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Necessity of ascorbic acid in the radioligand binding assay for [3H]5-hydroxytryptamine

โœ Scribed by J.W. Andresen; J.C. Shih


Book ID
118955391
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
736 KB
Volume
25
Category
Article
ISSN
0028-3908

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The effects of ascorbic acid and ascorbate-induced lipid peroxidation upon (3H)-5-HT binding were examined in total membrane fractions prepared from mouse cortex and hippocampus. Low concentrations of ascorbic acid promoted lipid peroxidation of membranes as assessed by malondialdehyde production re