𝔖 Bobbio Scriptorium
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Near-Infrared Optical Imaging of Protease Activity for Tumor Detection1

✍ Scribed by Mahmood, Umar; Tung, Ching-Hsuan; Bogdanov, Alexei; Weissleder, Ralph

Book ID
127322747
Publisher
The Radiological Society of North America
Year
1999
Tongue
English
Weight
155 KB
Volume
213
Category
Article
ISSN
0033-8419

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## Abstract Improvement in tumor detection using β€œsmart” probes in combination with microcatheter fluorescence thoracoscopy was evaluated in a mouse model. These imaging probes increase in fluorescence intensity after protease activation; cathepsin B is a major activator of the probes used in this