Near-infrared multichannel Raman spectroscopy toward real-time in vivo cancer diagnosis
✍ Scribed by Shoji Kaminaka; Toshiaki Ito; Hiroya Yamazaki; Ehiichi Kohda; Hiro-o Hamaguchi
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 232 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0377-0486
- DOI
- 10.1002/jrs.903
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✦ Synopsis
Abstract
Using a newly developed InP/InGaAsP multichannel detector, we developed a near‐infrared Raman spectroscopic system that can measure human tissues efficiently without interference from fluorescence. This enabled us to measure an in vivo Raman spectrum of live human tissue (skin) in 1 min using fiber probe optics. By applying this system to human lung tissues, we found that Raman spectroscopy makes a clear distinction not only between normal and cancerous tissues but also between two different types of lung carcinomas. The results indicate a promising future for the non‐invasive real‐time Raman diagnosis of cancers. Copyright © 2002 John Wiley & Sons, Ltd.