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Near-infrared determination of active substance content in intact low-dosage tablets

✍ Scribed by Pascal Chalus; Yves Roggo; Serge Walter; Michel Ulmschneider

Book ID
116901096
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
422 KB
Volume
66
Category
Article
ISSN
0039-9140

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Near-infrared spectrometry (NIR) was used to quantify metroprolol succinate in controlled release tablets. Metoprolol tablets were made according to an experimental design using different strengths around a central strength of 47.5 mg per tablet. A comparison was made between NIR in the diffuse refl