𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Nd:YAG laser therapy for palliation of recurrent squamous cell carcinomas in the oral cavity

✍ Scribed by Marcos B. Paiva; Keith E. Blackwell; Romaine E. Saxton; Michael Bublik; Carson D. Liu; Ana Amélia P. Paiva Paolini; Thomas C. Calcaterra; Dan J. Castro


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
135 KB
Volume
31
Category
Article
ISSN
0196-8092

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

Background and Objectives

The objective of this study was to evaluate the outcome of laser photo‐thermoablation for palliation of recurrent squamous cell tumors of the oral cavity.

Study Design/Patients and Methods

Seventeen patients were treated with the Nd:YAG laser (power output was 50 W) delivered through a curved oral handpiece.

Results

Ten patients are alive, 7 with tumor remission, and 3 with persistent disease with an average follow‐up of 16 months (range = 2–36). A total of 29 tumor sites received laser treatment with 17 (58%) completely ablated. Stratified by tumor site Nd:YAG treatment led to complete local response in 8/10 buccal mucosa, 2/5 retromolar trigone, 2/2 tongue, 2/5 gingiva, 1/2 floor of mouth, 2/4 hard palate.

Conclusions

Nd:YAG laser treatment of recurrent oral cavity squamous cell carcinoma can be performed safely and repeated as needed to achieve tumor palliation. However, extended follow‐up may be needed before convincing evidence of long‐term therapeutic benefits is obtained. Lasers Surg. Med. 31:64–69, 2002. © 2002 Wiley‐Liss, Inc.


📜 SIMILAR VOLUMES


Salvage treatment for recurrent squamous
✍ Glenn J. Schwartz; Rajeev H. Mehta; Barry L. Wenig; Chitra Shaligram; Louis G. P 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB 👁 2 views

Background. Squamous cell carcinoma (SCCA) of the oral cavity recurs with a frequency of 25%-48%, a fact that usually portends a poor prognosis. Recent studies have reported salvage cure rates as high as 67%. Investigators have also claimed that restaging recurrent tumors provides useful prognostic

Salvage therapy in relapsed squamous cel
✍ Chun-Ta Liao; Joseph Tung-Chieh Chang; Hung-Ming Wang; Shu-Hang Ng; Chuen Hsueh; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 1 views

## Abstract ## BACKGROUND. Relapse of tumors in patients with oral cavity squamous cell carcinoma (OSCC) is associated with a poor prognosis. In addition, salvage therapy may be a significant source of morbidity in patients with relapsing OSCC. The objective of the current study was to determine p

Histopathologic parameters in the evalua
✍ Troels Bundgaard; Kristian Rossen; Søren D. Henriksen; Samih Charabi; Helmer Søg 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB 👁 1 views

## Background: Prognostic indicators that could assist in a more precise selection of patients with small oral carcinomas for differentiated therapy would be valuable. a significant fraction of patients with stage i disease have a relatively poor prognosis despite the small size of the tumor, but i

Prolonged survival and effective palliat
✍ David A. Karlin; Robert S. Fisher; Benjamin Krevsky 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 382 KB 👁 2 views

Endoscopic laser therapy provides effective symptomatic palliation for patients with squamous cell carcinoma of the esophagus. To investigate whether this treatment also prolongs survival, a retrospective case-control study was performed. Ten patients with squamous cell carcinoma of the esophagus, d