Background. Squamous cell carcinoma (SCCA) of the oral cavity recurs with a frequency of 25%-48%, a fact that usually portends a poor prognosis. Recent studies have reported salvage cure rates as high as 67%. Investigators have also claimed that restaging recurrent tumors provides useful prognostic
Nd:YAG laser therapy for palliation of recurrent squamous cell carcinomas in the oral cavity
✍ Scribed by Marcos B. Paiva; Keith E. Blackwell; Romaine E. Saxton; Michael Bublik; Carson D. Liu; Ana Amélia P. Paiva Paolini; Thomas C. Calcaterra; Dan J. Castro
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 135 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0196-8092
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✦ Synopsis
Abstract
Background and Objectives
The objective of this study was to evaluate the outcome of laser photo‐thermoablation for palliation of recurrent squamous cell tumors of the oral cavity.
Study Design/Patients and Methods
Seventeen patients were treated with the Nd:YAG laser (power output was 50 W) delivered through a curved oral handpiece.
Results
Ten patients are alive, 7 with tumor remission, and 3 with persistent disease with an average follow‐up of 16 months (range = 2–36). A total of 29 tumor sites received laser treatment with 17 (58%) completely ablated. Stratified by tumor site Nd:YAG treatment led to complete local response in 8/10 buccal mucosa, 2/5 retromolar trigone, 2/2 tongue, 2/5 gingiva, 1/2 floor of mouth, 2/4 hard palate.
Conclusions
Nd:YAG laser treatment of recurrent oral cavity squamous cell carcinoma can be performed safely and repeated as needed to achieve tumor palliation. However, extended follow‐up may be needed before convincing evidence of long‐term therapeutic benefits is obtained. Lasers Surg. Med. 31:64–69, 2002. © 2002 Wiley‐Liss, Inc.
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