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NDRG2 is highly expressed in pancreatic β cells and involved in protection against lipotoxicity

✍ Scribed by Lan Shen; Xuewu Liu; Wugang Hou; Guodong Yang; Yousheng Wu; Rui Zhang; Xia Li; Honglei Che; Zifan Lu; Yuanqiang Zhang; Xinping Liu; Libo Yao

Book ID
105759143
Publisher
Springer
Year
2010
Tongue
English
Weight
684 KB
Volume
67
Category
Article
ISSN
1420-682X

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## Abstract Pancreatic ductal adenocarcinoma is one of the most common causes of cancer death in the western civilization. Recently, NF‐κB has been shown to be activated in pancreatic ductal adenocarcinoma through constitutive activation of IκB kinase (IKK). Inhibition of NF‐κB by a super‐inhibitor