NBS1 is required for IGF-1 induced cellular proliferation through the Ras/Raf/MEK/ERK cascade

Raf-1 signaling is required for the late

Raf-1 signaling is required for the later stages of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cells but is not mediated by the MEK/ERK module

✍ Xuening Wang; George P. Studzinski 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

## Abstract We are interested in determining the signaling pathways for 1,25‐dihydroxyvitamin D~3~ (1,25D)‐induced differentiation of HL60 leukemic cells. One possible candidate is Raf‐1, which is known to signal cell proliferation and neoplastic transformation through MEK, ERK, and downstream targ