Navigating the epigenetic landscape of pluripotent stem cells
β Scribed by Li, Mo; Liu, Guang-Hui; Belmonte, Juan Carlos Izpisua
- Book ID
- 111950512
- Publisher
- Nature Publishing Group
- Year
- 2012
- Tongue
- English
- Weight
- 839 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm3393
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract As well as having the remarkable ability to differentiate into all of the cell types in the embryo, embryonic stem (ES) cells also have the capacity to divide and selfβrenew. Maintenance of pluripotency through repeated cell divisions indicates that the developmental plasticity of ES ce
Studies using high-resolution genome-wide approaches have recently reported that genomic and epigenomic alterations frequently accumulate in human pluripotent cells. Detailed characterization of these changes is crucial for understanding the impact of these alterations on self-renewal and proliferat