Nature and frequency of respiratory involvement in chronic progressive external ophthalmoplegia
β Scribed by Bart W. Smits; Yvonne F. Heijdra; Femke W. A. Cuppen; Baziel G. M. van Engelen
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 178 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0340-5354
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Eleven patients suffering from chronic progressive external ophthalmoplegia (CPEO) were investigated by means of electroretinograms (ERG) and visually evoked cortical potentials (VECP) to flash and checkerboard-reversal stimuli. One patient exhibited a Kearns syndrome, in two patients fundoscopy rev
Sixteen members of a family with a history of autosomal dominant progressive external ophthalmoplegia (adPEO) with hypogonadism were examined. The muscular involvement commenced cranially and descended in relation to increasing disease duration. The neuromuscular signs were PEO, dysarthria, dysphoni