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Natural selection on protein-coding genes in the human genome

✍ Scribed by Bustamante, Carlos D.; Fledel-Alon, Adi; Williamson, Scott; Nielsen, Rasmus; Todd Hubisz, Melissa; Glanowski, Stephen; Tanenbaum, David M.; White, Thomas J.; Sninsky, John J.; Hernandez, Ryan D.

Book ID
109895387
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
777 KB
Volume
437
Category
Article
ISSN
0028-0836

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The occurrence frequencies of bases A, C, G and T, denoted by \(a, c, g\) and \(t\), respectively, in 1487 human: protein coding sequences have been calculated and analyzed. The analysis has been performed by a diagrammatic method presented recently, in which each coding sequence is represented by a