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Natural killer cell activity in families of patients with systemic lupus erythematosus: demonstration of a killing defect in patients

✍ Scribed by M. R. J. Green; A. S. M. Kennell; M. J. Larche; M. H. Seifert; D. A. Isenberg; M. R. Salaman


Book ID
108699149
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
160 KB
Volume
141
Category
Article
ISSN
0009-9104

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Sera obtained from fifty-five patients with active systemic lupus erythematosus (SLE) and from four patients with mixed connective tissue disease (MCTD) previously shown by immunofluorescence and by double immunodiffusion to possess antinuclear antibodies, were tested for the presence of natural ant

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## Abstract ## Objective To determine whether there is a link between the frequency of natural killer T (NKT) cells and high levels of IgG in patients with systemic lupus erythematosus (SLE) and their relatives. ## Methods Blood samples were obtained from patients with SLE, their first‐degree re