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Natural inhibitors of indoleamine 3,5-dioxygenase induced by interferon-gamma in human neural stem cells

✍ Scribed by S. Chen; R. Corteling; L. Stevanato; J. Sinden

Book ID
119194682
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
832 KB
Volume
429
Category
Article
ISSN
0006-291X

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## Abstract Indoleamine 2,3‐dioxygenase (IDO), a tryptophan‐catabolizing enzyme, is an intracellular enzyme possessing various immunosuppressive properties. Here, we report the possible use of this enzyme to suppress proliferation of immune cells cocultured with IDO‐expressing fibroblasts of an all