Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by the formation of cartilage capped prominences that develop from the epiphyses of the long bones. EXT is heterogeneous with three different locations currently identified on chromosomes 8,11, and 19. Recently, we i
Natural history study of hereditary multiple exostoses
β Scribed by Wicklund, C. Luckert ;Pauli, R. M. ;Johnston, D. ;Hecht, J. T.
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 474 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Pseudoachondroplasia (PSACH) is a wellcharacterized autosomal dominant dwarfing condition. A great deal of information is available about orthopedic complications, but little is known about extraskeletal complications in adulthood. This study was undertaken to delineate the natural history of PSACH
Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by growth of benign bone tumors. Three chromosomal loci have been implicated in this genetically heterogeneous disease: EXT1 at 8q24, EXT2 at 11p13, and EXT3 on 19p. EXT1 and EXT2 were recently cloned. We evaluated 3