Chronic hepatitis B virus (HBV) infection has a complicated course. Three phases are identified: an immune tolerant phase with high HBV DNA and normal alanine aminotransferase (ALT) levels associated with minimal liver disease; an immune active phase with high HBV DNA and elevated ALT levels with ac
Natural history of chronic hepatitis B virus infection: What determines prognosis after cirrhotic decompensation?
โ Scribed by Lai Wei
- Book ID
- 108951996
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 57 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0815-9319
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Hepatitis B virus DNA (HBV DNA) in serum was measured by a Spot hybridization technique in a consecutive series of 79 cases with chronic HBV infection from Taiwan. HBV DNA was found in 96.3% (52/54) of HBeAg-positive, 66% (2/3) with neither ABeAg or anti-HBe and in 63.6% (14/ 22) of anti-HBe positiv
## **Remarkable progress has been made in our understanding of the natural history of chronic hepatitis B virus (HBV) infection in the past 25 years. Availability of sensitive HBV DNA assays and application of sophisticated immunological techniques led to the recognition that HBV replication persi