Natural Compounds in Drug Discovery: Biological Activity and New Trends in the Chemistry of Isoquinoline Alkaloids
โ Scribed by V. G. Kartsev
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 8 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v
## Abstract Several sโtriazoles **2, 7a, 10, 12**; sโtriazolo[3,4โb][1,3,4]thiadiazines (**3โ5**); sโtriazolo[3,4โb][1,3,4]thiadiazoles (**6, 8, 11, 15**); and sโtriazolo[3,4โb][1,3,4]thiadiazepine (**14**) were synthesized starting from 2โ(6โmethoxyโ2โnaphthyl)propanoic acid (**1**) (Naproxen). Th
## Abstract Metabolic activation of drug candidates to electrophilic reactive metabolites that can covalently modify cellular macromolecules may result in acute and/or idiosyncratic immune systemโmediated toxicities in humans. This presents a significant potential liability for the future developme