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Natural and experimental models of environmentally induced neurodegeneration: Implications for Alzheimer's disease

Book ID
122946502
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
362 KB
Volume
13
Category
Article
ISSN
0197-4580

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## Abstract Amyloid beta protein (AΞ²)‐related death‐inducing protein (AB‐DIP) is a novel AΞ² binding protein expressed ubiquitously. Here we demonstrate that overexpression of AB‐DIP in SH‐SY5Y neuroblastoma cells causes G2/M arrest. By deletion mutant analysis, we have identified the minimal region