Currently natriuretic peptides are justifiably regarded as the most promising circulating markers of cardiovascular disease in dogs and cats, but there are many other markers that can be used in the evaluation of such patients. There are markers of myocyte injury typified by troponins I and T; marke
Natriuretic peptides in cardiovascular diseases
✍ Scribed by Mariusz Piechota; Maciej Banach; Anna Jacoń; Jacek Rysz
- Book ID
- 111490405
- Publisher
- SP Versita
- Year
- 2008
- Tongue
- English
- Weight
- 593 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1425-8153
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✦ Synopsis
Abstract
The natriuretic peptide family comprises atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP), and urodilatin. The activities of natriuretic peptides and endothelins are strictly associated with each other. ANP and BNP inhibit endothelin-1 (ET-1) production. ET-1 stimulates natriuretic peptide synthesis. All natriuretic peptides are synthesized from polypeptide precursors. Changes in natriuretic peptides and endothelin release were observed in many cardiovascular diseases: e.g. chronic heart failure, left ventricular dysfunction and coronary artery disease.
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