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Natriuretic peptides in cardiovascular diseases

✍ Scribed by Mariusz Piechota; Maciej Banach; Anna Jacoń; Jacek Rysz


Book ID
111490405
Publisher
SP Versita
Year
2008
Tongue
English
Weight
593 KB
Volume
13
Category
Article
ISSN
1425-8153

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✦ Synopsis


Abstract

The natriuretic peptide family comprises atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP), and urodilatin. The activities of natriuretic peptides and endothelins are strictly associated with each other. ANP and BNP inhibit endothelin-1 (ET-1) production. ET-1 stimulates natriuretic peptide synthesis. All natriuretic peptides are synthesized from polypeptide precursors. Changes in natriuretic peptides and endothelin release were observed in many cardiovascular diseases: e.g. chronic heart failure, left ventricular dysfunction and coronary artery disease.


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