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Native analysis of plasma-derived clotting factor VIII concentrates: “Sponge effect” and contaminants

✍ Scribed by Barbara Blasi; Gian Maria D'Amici; Angelo D'Alessandro; Lello Zolla

Book ID
112083371
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
534 KB
Volume
33
Category
Article
ISSN
0173-0835

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Proteomic characterization of plasma-derived clotting factor VIII–von Willebrand factor concentrates
✍ James G. Clifton; Feilei Huang; Spomenka Kovac; Xinli Yang; Douglas C. Hixson; D 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 320 KB

## Abstract Proteomic methods were used to identify the levels of impurities in three commercial plasma‐derived clotting factor VIII‐von Willebrand factor (FVIII/VWF) concentrates. In all three concentrates, significant amounts of other plasma proteins were found. In Octanate and Haemoctin, two con