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Nasal irritation and pulmonary toxicity of aliphatic amines in mice

✍ Scribed by F. Gagnaire; S. Azim; P. Bonnet; P. Simon; J. P. Guenier; J. De Ceaurriz

Book ID
118284127
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
395 KB
Volume
9
Category
Article
ISSN
0260-437X

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Sensory and pulmonary irritation of aliphatic amines in mice: A structure–activity relationship study
✍ F. Gagnaire; S. Azim; P. Simon; B. Cossec; P. Bonnet; J. de Ceaurriz πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 505 KB

The expiratory bradypnea indicative of upper airway irritation in mice was evaluated during a 15-min oronasal exposure to increasing concentrations of sixteen aliphatic amines. The airborne concentration resulting in a 50% decrease in the respiratory rate of mice ( R D ~~) was calculated for each te