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Nasal absorption enhancement of insulin using PEG-grafted chitosan nanoparticles

โœ Scribed by Xinge Zhang; Huijie Zhang; Zhongming Wu; Zhen Wang; Haimei Niu; Chaoxing Li

Book ID
116437822
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
297 KB
Volume
68
Category
Article
ISSN
0939-6411

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Chitosan-NAC nanoparticles as a vehicle
Chitosan-NAC nanoparticles as a vehicle for nasal absorption enhancement of insulin
โœ Xin Wang; Chao Zheng; Zhongming Wu; Dayong Teng; Xinge Zhang; Zhen Wang; Chaoxin ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 465 KB

## Abstract The purpose of this work was to investigate chitosanโ€__N__โ€acetylโ€Lโ€cysteine (chitosanโ€NAC) nanoparticles as a potential carrier system for the nasal delivery of insulin. For the study, we used insulinโ€loaded chitosanโ€NAC nanoparticles (140โ€“210 nm in diameter) prepared by __in situ__ ge